By Jeff Balke
By Ben DuBose
By Ben DuBose
By Sean Pendergast
By Sean Pendergast
By Calvin TerBeek
By Jeff Balke
By Jeff Balke
In a March 2012 case report for the Journal of Neurosurgery, a Salt Lake City physician wrote of an 83-year-old man who was rushed to the emergency room after falling at home. He had started taking dabigatran a month earlier. The case echoes the claims made by Franklin's daughters: After two hours, the man's speech slurred; after six hours, CT scans showed extensive intracranial hemorrhaging. Not long after, he died.
"Patients treated with dabigatran are often elderly individuals with multiple comorbidities," the case study states. "Imbalance and falls are common in this population, and intracranial hemorrhage resulting from minor trauma may occur with increasing frequency as use of this drug becomes more widespread."
In April 2012, The Institute for Safe Medication Practices claimed that for the first quarter of 2011, dabigatran accounted for a higher total of serious adverse events than any other drug the group monitored, with the exception of a drug used to treat a rare lung disorder.
The institute's report states that when representatives for Boehringer were contacted, they "also observed the large volume of serious adverse event reports for its new drug, but noted that bleeding was a known risk of anticoagulant drugs, and substantial warnings were in place. The company attributed the report volume in part to the rapid acceptance of the drug into the market and an active sales force with extensive contact with physicians, resulting in more frequent reports."
It's that "active sales force" that convinced so many doctors of Pradaxa's benefits by neglecting to mention the irreversibility, attorney Watts says. He says doctors are not to blame and that the responsibility lies with a manufacturer that chose "sales over responsible disclosures."
And Watts's conspiracy theory — that Boehringer knowingly marketing a faulty product — has the proceeds from those sales vastly outweighing any damages from litigation.
"The lawsuits are a small pimple on the ass of huge profits that come from selling a drug like this," he says.
Franklin's daughters say being part of the lawsuit is something their mother would have wanted.
"I don't want other people to go through what we just went through," Hormann says. "And I know that my mom would feel the same."
Recalling how her mother was devoted to her students and how she tried not to complain to her family about whatever pain she may have been suffering, Salazar echoes her sister. Fighting to pull Pradaxa off the market is the "one thing she would want us to be doing," Salazar says. "Because she was such a caregiver for everyone."
There is an antidot to Pradaxa-Dagibatram.It is:Carboxocobalamin-Vitamer of Vitamin B12.
It is used,and reported to be effective in the case of Cyanide poisioning.References:Pubmed.
No reason why it should not be effective in Pradaxa-Dagibatram intoxication.
My 91 yr old Grandmother was given Pradaxa by a "top" cardiologist as if it were no problem,in fact mentioned unlike coumadin which she had been on 7 yrs prior , but moved and a Dr removed it. She was a pistol! I drove her everywhere so thats how i know this so well, There were 4 salesman with lunchs and golf tickets and speaking fees etc! I listened. Anyways in days she cant ge tout of bed!
I take her to the emergency room and she needed 4 blood and 2 plasma and ICU for weeks several times, transfusions, endless, she has many things now she neverhad, cant enjoy shopping,sleeps all the time, cant eat right, gets along on ensures they help. A GI said it was insanity to give a 90 yr old a drug with no antidote, how can a 1 size for all dose go unmonitored? especially if no antidote exists!!! I guess they figure oh well nothing we can do why check it?? everyone over 80 died or almost did and was destroyed by it making her almost helpless now.
I just don't get it, if a drug maker makes a blood thinning drug and fails to tell people that there is no antidote, how can people think something is wrong for suing the maker. For crying out loud - people die from this, while the maker generate billions of dollars and its considered frivolous to sue for the damages, injuries and lost life? No way! Kill my family & your going to pay, a corporation is basically a person now and the only way to punch them while hopefully creating a safer future is to take their money!
My the lord be with you... I lost my daddy june 23 2012.... He was on this medication for nine months.... He was bleeding inside from the chest down... No way to stop it.... I will pray for you..... Good luck
My daddy died june 23 2012 he too died from bleeding internally from this medication .. he was only 73.... They tried everything even dialysis..... He bled to death .....so yes this medication needs to go before many more people die from it... We had no warnings... So swiftright you are so wrong to pass judgement ... Hope you never lose a loved one like this.. your life will never be the same
80 year old hit head after fall and ended up with a concussion and the kids think she would have probably left the hospital with a "slight head ache"? Come on, ppl get old and they die. This is not a good example of why we need to remove a drug from the market.
Really!?!? You noticed your mom was pale and weak, but you didn't ask her to go to the doctor? This is a case of lack of education. If you put a medication...which is a chemical...in your body and do not report abnormal symptoms to your doctor, you are not only ignorant, but terminally stupid. Get a grip, stop suing for everything, and take responsibility for your own health. Be proactive in your approach, and ALWAYS BE HONEST with your doctor. This is coming from an ER nurse with 12 years of experience.
As soon as you skip that first salad, you are at a greater risk of bleeding. It's dangerous when doctors dose Coumadin according to a patient's "routine".
If you did your "homework" you would find that pharma companies do not, under any circumstances, send physicians on trips. In fact, pens aren't even allowed as of 2009. But brownie points for basing your health decisions on your independent Internet "research" as opposed to your formally educated healthcare providers.
You only left out a few things:(1) Warfarin interacts with quinolones (Levaquin and Cipro being the best-known), which are THE most popular antibiotic class around these days for things from bladder infections to sinusitis and pneumonia. Good ol' Doc gets a call from Miz Patient about that sinus trouble coming back, the anticoagulation goes out of control and guess what, here comes a major GI bleeding episode.(2) The medical literature says you can "probably" neutralize Pradaxa via dialysis. Say WHAT? Dialysis requires putting a big honkin' arterial-venous catheter in that carries major bleeding risks of its own.(3) As Obi-Wan said, "There is another". Lovenox is the third alternative for anticoagulation, and it wears off in 6-8 hours. But you have to give it via injection just like insulin and it costs a fortune.Thanks for putting this in front of the public.Stella Fitzgibbons, MD, FACP
I am a Pradaxa user and I have a point of view I hope gets considered.
At the relatively young age of 55 a routine physical revealed AtrialFibrillation. I was put on Warfarin but was never able to arrive at astable level. My pro thrombin time was all over the place. Thisnecessitated frequent testing. My veins quickly developed scars so Ibecame a difficult customer at the phlebotomist. It was a littleunpleasant.
Driving to the testing lab became a significant part of my routine. Iwonder if the expense and increased potential for mishap are figuredinto the statistics of any comparison study between Warfarin andPradaxa.
As a child I was no fan of leafy green vegetables, but when I got myadult taste buds that changed. From my 20s through my mid 50s I ateeverything green. Once I was put on Warfarin that had to stop.
I wonder how statisticians can account for the removal of leafy greenvegetables from the diet of a whole class of drug users. It’s not justthe vitamin K that you are missing. There are countless compoundsinvolved. Some of them help prevent the diseases we all become moreprone to as we age.
My cardiologist switched me to Pradaxa over a year ago. I can eat whatI want to eat again and feel better for that. I no longer have to wearlong sleeved shirts all the time to hide the bruising that comes withconstant testing. I am very fortunate that my insurance picks up mostof the cost of Pradaxa as it is ridiculously expensive.
The dietary factor; the statistical dangers of travel and the generalquality of life are all considered by the physician when he suggestschanging from one drug with drawbacks to another drug with differentdrawbacks. I don’t believe that he is snowed at all by the prettysales rep that talks up Pradaxa. He does the math; but his mathaccounts for some variables that aren’t well considered in groupstudies.
I’m not even 60 yet. Hopefully something better than Pradaxa will comealong soon. In the meantime I want to continue taking it. I think Iwill live longer and better than I would if I were forced back toWarfarin.
( http://fashion-long-4biz.com )Cheapest (TOP) Nike,Air Max, Jordan (1-24) shoes $31UGG BOOT $50Nike shox (R4, NZ, OZ, TL1, TL2, TL3) $31T-shirts (polo, ed hardy, lacoste) $15Wig $22Handbag(LV,Chanel,Coach,DG,ED Hardy.etc.)$30Jean (True Religion, ed hardy, coogi)$30Sunglasses (Dior, Oakey, coach, Gucci, Armaini)$16jersey $ 29 New era cap $16 Belt(ED hardy /LV) $15Watch(Rolex) $80 Scarf $21Bikini (Ed hardy, Polo,Gucci,LV,Christan Audigier,Affliction) $15Accept electronic bank transfer, credit card payment.Free Shipping( http://fashion-long-4biz.com )( http://fashion-long-4biz.com )
I have atrial fibrillation. A well-known electrophysiologist tried to get me to switch from my $5 per month tried and true Coumadin (prescribed by my cardiologist) that has worked very well for me, to $280 per month Pradaxa. I did my homework and found out about the "no antidote" problem. I promptly told him to pound sand. I also got a new EP. You would think that his drug-company sponsored Carribean or European vacation were riding on my decision. Oh wait...
Big pharma keeps using lower rates of bleeding as an argument for Pradaxa, but that doesn't change the fact that there is no cure for it. It's easy to brush it off as a statistic until it actually happens to somebody...
#PRADAXA BLEEDS raise concerns. More www.pradaxableeds.com Should #FDA #recall?
As a geriatric social worker I am very confirmed about seniors on pradaxa. See pradaxahelpline.com
as Frances said I am dazzled that anyone able to get paid doller5846 in four weeks on the internet. have you read this
as Sherry responded I didn't know that anyone able to make doller4064 in a few weeks on the internet. have you read this
Joseph Stalin was asassinated using Warfarin. Now that's what I call a real rat poison and I'm sure the rats would agree.
My Grandmother received a informative brochure to read after we got her back from the 1st of 3 transfusions and icu stays and nothing but transfusions help.
Precisely my experience, but she is alive,just too weak to enjoy life normally now and bleeds chronically.
@Swiftright Right. Yeah effing right!!! My grandmother just died from this drug! There was nothing wrong with her until she took this poison and then she dies a couple months later from internal bleeding and kidney failure! All the side effects from the drug! They failed to make no antidote to stop the bleeding. As long as there making billions is all they care about. There are truelly devils walking his earth and the makers boelinger ingalham are one of them. It's people like u who put too much faith in the crooked government! They use humans as labrats and to become richer! Go ahead and give this pradaxa to your loved one and watch them die a month or two later. And then let's see how u feel then. Ignorance is a bliss! Good day!
I understand that, but My Grandmother was shopping 4 hours easily until this now cant go 20 minutes and needs a walker as she is dizzy all the time, headaches etc.
It almost killed her 3 two week ICU stays with numerous pints of blood and plasma, 6 the first stay alone, and transfusions inbetween. I have to be there for here every day, Which I do, but it ruined her life and health! she hads money to do anything but cant!
Nice try, but swing and a miss, I myself had called my Grandmothers cardiologist and internist, both of whom said it was to be expected and her next appt was in a few days blah blah, I read that she should have bee on hospitalized because of this drug and another one with this, I forget the name, and was sent home and calls were not ignored, just misdiagnosed and bad advice was given.. The Hospitalist that saw My grandmother asked about DNR and etc! He had never seen Pradaxa or an overdose , which he said this was!
@Singlebifem26 ? Bitch if ur were my nurse u unsympathetic miserable person I would smack the ignorant out of you. Don't come on here blaming people for trusting what there doctors prescribed them to get better. I hope u lose some one u care about due to a drug that the doctor prescribes them. Now do everybody a favor and crawl in a hole and never come out! Good day!
I am an EMT, My Grandmother is very much pto active about her health being almost vegan, walked 3 miles a day briskly and now cant without a walker!
The hospitalist was shocked! he never saw pradaxa ever yet and no overdose either and said he could do only a few things and started talking DNR!!!
It happens fast and with elderly its not that easy until late. SHAME ON YOU SIR! I WOULD SLAP YOUR FACE.
My daddy tried.... The doctors wouldnt listen... When they finally did it was too late.....again please dont pass judgement unless you have lived the nightmare i did.... Watching your father die and you cant help and there is no reversal makes your heartache
If you had any clue about the medical field you would know that direct drug marketing to MDs and PharmDs is alive and well in 2012.
While on Warfarin (from age 42 - 44), my cardiologist told me I could eat the leafy greens I enjoy...but just to do it consistently. With good monitoring and a consistent diet, we were able to keep me on my salads and keep my levels stable enough that it wouldn't cause a bleeding issue. If you consider going back to Warfarin, you might want to check with your doctor about that.
MY GRANDMOTHER WAS 90 THEN WILL BE 92 SOON!
SHE WENT VEGETARIAN 90% IN THE 1970'S AND WAS ALWAYS EXERCISING WALKING DAILY VERY BRIKLY, AND IS DESTROYED BY LACK OF BLOOD ALL THE YIME! HEADACHES , ITS BAD AND SAYING NO MONTORING IS GREAT CRITICAL THINKING THERE.
She was a very healthy 80. She did aerobics everyday and walked and enjoyed life. She had 10, 15, 20 more years to enjoy her kids and grandkids. Age is relative.
Actually she could have died today, tomorrow, next week, or the day after next Friday. She could have smoked weed and cigarettes daily and lived to be 116. Go figure.