In compiling a list of the best Bond baddies, one has to establish a few parameters. For starters, you must take into account the bad guy's ultimate objective, weighting plans for global conquest/destruction more heavily than mere monetary gain. Then there are more esoteric factors, like background, motivation, and even hair (or lack thereof). The end results shake out thusly:
5. Frank Sanchez (Robert Davi) - License to Kill (1989)
Diabolical Plot: Make a shitload of money selling cocaine.