See more pics of the blaze in our slideshow.
A fire broke out just after midnight at Simpson Galleries, a fine art and antiques dealer on Main and Isabella in Midtown. The gallery is just near the popular music spots Continental Club and The Mink.
This blaze marks the third time a local antique store has gone up in smoke in the last year, starting with the fire that nearly destroyed Agora Cafe and its neighboring antique store last Halloween. In June, another fire struck at another antique store on the same block as Agora, and officials deemed that blaze "suspicious."
Several trucks responded to this morning's blaze at Simpson Galleries. Officials say there were no apparent injuries. The fire was contained to the store, which suffered extensive damage.
We'll update with more information as we get it.